June 27, 2018 from 1 p.m. to 2 p.m.
Hess Center for Science & Medicine 1470 Madison Avenue
2nd Floor, Seminar Room A
- Frank Bengel, PhD
- Professor and Director Department of Nuclear Medicine Hannover Medical School
Abstract: This talk will focus on targeted radionuclide- based molecular imaging techniques, which enable whole- body assessment of biologic mechanisms and hence may be used for interrogation of the heart-brain axis. The effects of injury in one organ can be studied alongside with systemic activation and involvement of the other organ. Inflammation appears to be of particular importance in establishing systems-based networking links among heart and brain (and other organs) in degenerative disease, and it can be modified therapeutically to achieve improved repair and regeneration. The focus is on an improved understanding of mechanisms of repair and of systems- based inter-organ interaction. The vision is that early imaging of those mechanisms may be used to predict risk of subsequent degeneration and that this may guide targeted interventions – ideally by using the same molecular pathway – in order to achieve improved outcome not only for the primary organ but also for other interconnected organs.