July 21, 2015 from 11:15 a.m. to 12:15 p.m.
Hess Center - 1st Floor
TMII Large Conference Room 117
- Junghwan Kim, (PhD candidate)
- University of Pittsburgh, PA
Abstract: MRI is known as non-invasive imaging modality that provides superb anatomical soft tissue details than any other imaging modalities that are used in medical field. Over a decade, researches in UHF (ultra-high-field)-MRI have been widely studied to further improve the technology and understand the diseases. With the increased SNR provided by UHF-MRI (≥7T), have tapped many studies to focus on developing RF coil designs and its performance to preserve provided high SNR and produce uniform EM (electromagnetic) field; particularly, transmit array designs and receive array insert designs. B1+/RF-shimming has also been studied to produce homogeneous B1+ field and lower the power deposition in tissues by manipulating amplitudes/phases and RF envelops. X-nuclei MRI has been known to provide pathophysiological tissue alteration, however, its SNR is too low at clinically available MRI (3T≥).
X-nuclei studies at UHF-MRI are emerging nowadays since two folds of SNR increase (compare to 3T MRI) is guaranteed at 7T MRI. High sensitivity of UHF-MRI is used to investigate early biomarker for disease progress and confirmation based on T1-/T2-weighted, Gadolinium contrast and MT (magnetization transfer) proton MRI as well as utilizing unique response of X-nuclei MRI in various organs. Despite these promising advantages at UHF MRI, there are obstacles that hinder the performance of UHF-MRI, which are 1) B1+ field inhomogeneity and 2) Assurance and predictability of global/local power deposition in tissue as well as 3) Low SNR and co-registration in non-proton MRI.
In the presentation, dual-tune RF coil developed at 3T and 7T MRI for various part of the body will be presented as well as the numerical simulation of EM field behavior using FDTD method within the breast tissue will be summarized.